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IL1A — PPARG

Text-mined interactions from Literome

Stewart et al., BMC molecular biology 2007 : The objective of this study was to determine whether the suppressive effects of IL-4 on the IL-1 induced expression of MMP-3 involve activation of lipoxygenase and/or PPARgamma
Afif et al., Arthritis Res Ther 2007 (Osteoarthritis) : Specific inhibitors of the mitogen activated protein kinases ( MAPKs ) p38 ( SB203580 ) and c-Jun N-terminal kinase ( SP600125 ), but not of extracellular signal regulated kinase ( PD98059 ), prevented IL-1 induced downregulation of PPARgamma1 expression ... The IL-1 induced downregulation of PPARgamma expression might be a new and additional important process by which IL-1 promotes articular inflammation and cartilage degradation