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MMP8 — PTGS2

Text-mined interactions from Literome

Dickens et al., J Pediatr Hematol Oncol 2003 (Bone Neoplasms...) : Tumor development and growth were measured following treatment with a COX-2 inhibitor ( celecoxib ), an MMP inhibitor ( doxycycline ), or both
Okada et al., Anticancer Res 2005 : Bis-EUG, MMP and bis-MMP inhibited COX-2 gene expression at concentrations of 300 microM, 500 microM and 500 microM, respectively
Spinella et al., Cancer Res 2007 (Melanoma...) : Moreover, COX-1/COX-2 inhibitors block ET-induced PGE ( 2 ) and VEGF secretion, matrix metalloproteinase ( MMP ) activation, and cell invasion, indicating that both enzymes function as downstream mediators of ET-induced invasive properties
Lee et al., Exp Mol Med 2007 (Bone Neoplasms...) : Selective COX-2 inhibitors, NS-398 and celecoxib, inhibited cell proliferation and abrogated the enhanced mobility, invasiveness and MMP activities induced by COX-2 overexpression
Vardar-Sengul et al., J Periodontol 2008 (Alveolar Bone Loss...) : Selective cyclooxygenase-2 inhibitor, prophylactic omega-3 fatty acid, and a combination of these two agents can inhibit gingival tissue MMP-8 expression
Khan et al., J Immunol 2012 : In the current study, we determined whether MMP induced cyclooxygenase-2 expression was coupled to the expression of prostaglandin E synthase family members