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Qu et al., Urol Oncol 2010
(Urinary Bladder Neoplasms) :
MS-275 and
TSA significantly increased the level of histone acetylation, induced p21CIP1WAF1 mRNA expression, and
inhibited cyclin A mRNA expression, though no significant effect was observed on cyclin E. Bcl-2 expression was down-regulated, while bax expression was up-regulated
Jin et al., Tissue Eng Part A 2013
:
We observed that
TSA increased the expression of
proliferating cell nuclear antigen and cyclin D1 in hDPSCs at a certain concentration and the activation of JNK/c-Jun pathway was essential for TSA dependent hDPSC proliferation