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BRCA1 — CDK9

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: CDK9 — BRCA1 (direct interaction, two hybrid) Woods et al., Science signaling 2012

Text-mined interactions from Literome

Ouchi et al., Proc Natl Acad Sci U S A 2000 : After IFN-gamma treatment, induction of the cyclin dependent kinase inhibitor, p21WAF1, was synergistically activated by BRCA1 , whereas the IRF-1 gene was unaffected
Moisan et al., J Biol Chem 2006 : Here, we investigate the effect of BRCA1 on serine 2 phosphorylation and UV-activated P-TEFb kinase activity ... We now show that BRCA1 inhibits immunoprecipitated P-TEFb kinase activity from UV-irradiated cells and preferentially decreases UV-induced serine 2 phosphorylation of soluble, rather than chromatin bound, RNAPII