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CASP1 — IL1RN
Text-mined interactions from Literome
Sumitomo et al., Br J Cancer 1999
:
Overexpression of the secretory type
IL-1ra with adenovirus vector ( AxlL-1ra )
enhanced ICE gene expression, while exogenous IL-1ra ( 100 ng ml(-1) ) did not enhance it
Maedler et al., Proc Natl Acad Sci U S A 2004
(Diabetes Mellitus, Type 2) :
Antagonizing
IL-1Ra by introduction of small interfering RNA to IL-1Ra into human islets
led to
caspase-3 activation, DNA fragmentation, and impaired beta cell function
Maron-Gutierrez et al., Eur Respir J 2011
(Pulmonary Fibrosis...) :
Nevertheless,
caspase-3 , IL-1ß, IL-1a,
IL-1RN and TGF-ß mRNA expression
diminished after cell therapy