Lee et al., Biochem Biophys Res Commun 2005
:
These TNF-alpha- or INF-gamma induced augmentations of LPS response and TLR4 expression were all down-regulated by differentiation
Lin et al., J Am Soc Nephrol 2012
(Diabetes Mellitus, Experimental...) :
Silencing of TLR4 with small interfering RNA attenuated high glucose induced I?B/NF-?B activation, inhibited the downstream synthesis of IL-6 and CCL-2, and impaired the ability of conditioned media from high glucose treated proximal tubule cells to induce transmigration of mononuclear cells