Mathai et al., Oncogene 2002
:
E1A depended on wild-type p53 to induce BIK and activate the death program
Happo et al., Cell death & disease 2012
(Lymphoma) :
Moreover, although p53 mediated induction of Bik has been reported, neither Eµ-Myc/Bik ( -/- ) nor Eµ-Myc/Bik ( -/- ) Noxa ( -/- ) lymphomas were more resistant than control Eµ-Myc lymphomas to killing by DNA damaging drugs, either in vitro or in vivo