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MSTN — PPARA
Text-mined interactions from Literome
Li et al., Cell Biol Int 2011
(MAP Kinase Signaling System) :
Here, we demonstrated that
myostatin inhibited 3T3-L1 preadipocyte differentiation into adipocyte by
suppressing C/EBPa ( CCAAT/enhancer binding protein a ) and
PPAR? ( peroxisome-proliferator activated receptor ? ), also activated ERK1/2 ( extracellular-signal regulated kinase 1/2 )
Lei et al., Sci China Life Sci 2011
:
Expression patterns of adipogenic transcription factors showed that exogenous
myostatin suppressed
PPAR?2 and aP2 expression ( P < 0.01 ), while supplemental arginine or myostatin antibody promoted ADD1 expression ( P < 0.01 )