Mackova et al., Endocrinology 2000
:
Furthermore, inhibition of p42/44MAPK phosphorylation had no effect on p38MAPK activation
Conejo et al., J Cell Physiol 2001
(MAP Kinase Signaling System) :
This mitogenic effect of insulin was precluded by inhibition of p70S6-kinase ( either by rapamycin or by the PI3-kinase inhibitor LY294002 ) as well as by inhibition of p44/p42-MAPK with PD098059, but was not affected by inhibition of p38-MAPK Ho et al., Mol Cell Endocrinol 2006
:
Studies with selective MAPK inhibitors reveal a modulating effect of MAPKs on arylalkylamine-N-acetyltransferse ( AA-NAT ) activity, with involvement of p42/44MAPK in the induction of AA-NAT and p38MAPK participating in the amplitude and duration of the AA-NAT response