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PRDX1 — TXN

Pathways - manually collected, often from reviews:

• Reactome Reaction: PRDX1 → TXN (reaction) Yamashita et al., J Biol Chem 1999*, Lee et al., J Biol Chem 2007*, Nagy et al., J Biol Chem 2011*

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: PRDX1 — TXN (physical association, affinity chromatography technology) Junn et al., J Immunol 2000*
• IRef Intact Interaction: Complex of 34 proteins (association, tandem affinity purification) Pichlmair et al., Nature 2012
• IRef Intact Interaction: Complex of 168 proteins (association, cross-linking study) Byron et al., Proteomics 2012
• IRef Intact Interaction: TXN — PRDX1 (physical association, cross-linking study) Schwertassek et al., EMBO J 2007*

Text-mined interactions from Literome

Broin et al., Plant Cell 2002 : The plastidic 2-cysteine peroxiredoxin is a target for a thioredoxin involved in the protection of the photosynthetic apparatus against oxidative damage
Hoshino et al., Am J Respir Crit Care Med 2003 (Disease Models, Animal...) : Thioredoxin (TRX) is a multifunctional redox ( reduction/oxidation ) -active protein that scavenges reactive oxygen species by itself or together with TRX dependent peroxiredoxin