Gene interactions and pathways from curated databases and text-mining

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IGF1R — SORBS1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: Complex of CBL-SORBS1 → IGF1R (increases, IGF1R Translocation, CBL/SORBS1 Activity)
    Evidence: Upon phosphorylation, the Cbl-CAP complex translocates to lipid raft domains in the plasma membrane, mediated by the interaction of the SoHo domain of CAP with the protein flotillin50.