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IL10 — MAF
Text-mined interactions from Literome
Cao et al., J Immunol 2002
(Fibrosarcoma) :
Differential
regulation of IL-12 and
IL-10 gene expression in macrophages by the basic leucine zipper transcription factor
c-Maf fibrosarcoma
Cao et al., J Immunol 2005
:
In this study, following up on our previous novel finding that the protooncogene c-Maf of the basic leucine zipper family of transcription factors is expressed in monocytes and macrophages, we investigate the
role of
c-Maf in the transcriptional regulation of
IL-10 and the underlying molecular mechanism in macrophages ... Ectopic expression of
c-Maf stimulates not only exogenously transfected IL-10 promoter-driven luciferase activity in a dose dependent manner but also
enhances endogenous
IL-10 gene expression stimulated by LPS
Xu et al., J Immunol 2009
:
c-Maf regulates
IL-10 expression during Th17 polarization ... TGFbeta was also synergistic with IL-27 to induce
c-Maf , and it
induced Stat1 independent
IL-10 expression in contrast to IL-27 alone
Apetoh et al., Nat Immunol 2010
:
The transcription factor
c-Maf is
essential for the induction of
IL-10 by Tr1 cells, but the molecular mechanisms that lead to the development of these cells remain unclear