Tapia et al., Hum Reprod 2008
:
MMP2 and MMP9 secretion was not affected by LIF but LIF did increase secretion of TIMP-1 and -2 ( P < 0.001 versus control )
Harvey et al., Development 1995
:
Both LIF and EGF stimulated uPA and MMP-9 activity in blastocyst outgrowths after 3 days of culture ( day 7 )
Harvey et al., Hum Reprod 1995
:
Recent experiments show that both LIF and EGF stimulate secretion of urokinase-type plasminogen activator ( uPA ) and gelatinase B/matrix metalloproteinase-9 (MMP-9) in day 7 mouse blastocyst outgrowths
Richards et al., J Immunol 1993
(Neoplasms) :
The results suggest that OM as well as IL-6 and LIF , other cytokines acting through similar receptor pathways, may act to inhibit net MMP activity by specifically up-regulating TIMP-1 expression