Gene interactions and pathways from curated databases and text-mining

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AD5 — TP53

Text-mined interactions from Literome

Yang et al., J Virol 2002 (Adenovirus Infections, Human...) : Expression of the Ad5 E1A 243-aa protein resulted in proliferation stimulated p53 upregulation, while expression of the Ad5 E1A 289-aa protein led to DNA damage induced p53 activation
Cun et al., PloS one 2013 (Carcinoma, Hepatocellular...) : APE1 was strongly expressed in MHCC97L cells and was induced by irradiation in a dose dependent manner, and Ad5/F35-siAPE1 effectively inhibited irradiation induced APE1 and p53 expression
Wang et al., Cancer Gene Ther 1995 (Bone Neoplasms...) : By using immunocytochemical and Western blot analyses, we demonstrated that Ad5CMV-p53 effectively infected Saos-LM2 cells at multiplicities of infection of 10 to 50 plaque forming units/cell and mediated a high-level expression of the exogenous wild-type p53 protein in the cells