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AD5 — TP53
Text-mined interactions from Literome
Yang et al., J Virol 2002
(Adenovirus Infections, Human...) :
Expression of the
Ad5 E1A 243-aa protein
resulted in proliferation stimulated
p53 upregulation, while expression of the Ad5 E1A 289-aa protein led to DNA damage induced p53 activation
Cun et al., PloS one 2013
(Carcinoma, Hepatocellular...) :
APE1 was strongly expressed in MHCC97L cells and was induced by irradiation in a dose dependent manner, and
Ad5/F35-siAPE1 effectively
inhibited irradiation induced APE1 and
p53 expression
Wang et al., Cancer Gene Ther 1995
(Bone Neoplasms...) :
By using immunocytochemical and Western blot analyses, we demonstrated that
Ad5CMV-p53 effectively infected Saos-LM2 cells at multiplicities of infection of 10 to 50 plaque forming units/cell and
mediated a high-level expression of the exogenous wild-type
p53 protein in the cells