Lametschwandtner et al., J Allergy Clin Immunol 2004
(Dermatitis, Atopic) :
T-bet transfection also induced IL-12Rbeta2 and CXCR3 expression on human T ( H ) 2 cells, whereas the IL-18 receptor was only induced as a consequence of T-bet mediated increased responsiveness to IL-12
Agostini et al., Am J Respir Crit Care Med 2005
(Chronic Disease...) :
In vitro kinetic studies demonstrated that, although CXCR3 was rapidly induced by interleukin (IL)-15 and IL-18 , CXCR6 induction was slow ( 8 d ) and mainly regulated by IL-15
Schmitz et al., Brain Behav Immun 2013
:
Oppositely, CXCR3-deficiency had no protective effect after traumatic nerve injury but reduced EAE evoked hyperalgesia and was associated with reduced clinical EAE scores, a reduction of the pro-inflammatory cell infiltration and reduced upregulation of interferon gamma and interleukin-17 in the spinal cord