Gene interactions and pathways from curated databases and text-mining

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COL1A2 — IFNG

Text-mined interactions from Literome

Ghosh et al., J Biol Chem 2001 : Overexpression of p300 restored COL1A2 stimulation by TGF-beta in the presence of IFN-gamma , and potentiated IFN-gamma dependent positive transcriptional responses
Higashi et al., J Biol Chem 2003 : Also, overexpression of a deletion mutant YB-1, which lacks the carboxyl-terminal domain, abrogated the repression of COL1A2 transcription by IFN-gamma
Higashi et al., J Biol Chem 2003 : Down-regulation of endogenous YB-1 expression by double stranded YB-1-specific RNA abrogated the transcriptional repression of COL1A2 by IFN-gamma in the absence and presence of TGF-beta ... They also indicate that IFN-gamma/YB-1 inhibits COL1A2 transcription by dual actions : via the IFN-gamma response element and through a cross-talk with the TGF-beta/Smad signaling pathway
Xu et al., J Biol Chem 2004 : In this report, we demonstrate that CIITA is a key mediator of COL1A2 repression by IFN-gamma ... This leads to the alleviation of COL1A2 repression and MHC-II activation by IFN-gamma ... Our data suggest that CIITA is a crucial member of a repressor complex responsible for mediating COL1A2 transcription repression by IFN-gamma
Fang et al., Nucleic Acids Res 2009 : Here we demonstrate that TGF-beta abrogated COL1A2 repression by IFN-gamma through altering the relative expression of RFXB and RFXBSV