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GRAP2 — TGFB1

Text-mined interactions from Literome

Zhou et al., Zhonghua Yi Xue Za Zhi 2002 : Furthermore, the functional and structural results showed that Ox-LDL regulates rat TGF-beta(1) gene expression through AP-1 binding site and c-Jun/AP-1 complex, it gives rise to the involvement of protein kinase C, but not p38MAPK , in Ox-LDL induced TGF-beta(1) gene expression
Burt et al., Diabetologia 2003 : P38 mitogen activated protein kinase mediates hexosamine induced TGFbeta1 mRNA expression in human mesangial cells ... P38-MAPK inhibition using SB202190 ( 1 micro mol/l ) reduced hexosamine induced TGFbeta1 expression in normal and high glucose
Nakagawa et al., J Am Soc Nephrol 2005 : Whereas blocking of ERK1/2 or p38 failed to inhibit TGF-beta1 induced Smad2 activation, inhibition of Smad2 by Smad7 overexpression inhibited the phosphorylation of ERK1/2 but not p38 in response to TGF-beta1
Kim et al., Invest Ophthalmol Vis Sci 2005 : To evaluate the effects of TGF-beta1 and doxycycline on production of gelatinase MMP-9 and activation of Smad, c-Jun N-terminal kinase (JNK), extracellular regulated kinase (ERK), and p38 mitogen activated protein kinase ( MAPK ) signaling pathways in human corneal epithelial cells
Hu et al., Am J Physiol Heart Circ Physiol 2007 (Anoxia...) : TGF-beta(1) overexpression also blocked H-R mediated p38 and p44/42 MAPK activation
Mitu et al., American journal of physiology. Renal physiology 2007 (Diabetes Mellitus...) : In these cells, BMP7 effectively activates smad5 ( but not smad1 ) and raises p38 phosphorylation [ which is also increased by transforming growth factor-beta ( TGF-beta ) ]
Liu et al., Zhonghua Wai Ke Za Zhi 2007 (Bronchiolitis Obliterans...) : Further study in Smad3-deficient fibroblasts demonstrates that p38 and ERK1/2 could be activated by TGF-beta1 and result in fibroblast differentiation
Wang et al., Pharmazie 2009 : Fluorofenidone significantly reduced the phosphorylation of ERK1/2, P38 and JNK induced by TGF-beta1