Iwanaga et al., Oncogene 2004
:
Promoter analysis showed that the growth regulated expression of MLH1 and Rad51 genes was mainly mediated by E2F that plays crucial roles in regulation of DNA replication, suggesting close relation between some of the repair genes and DNA replication
Chen et al., Cell cycle (Georgetown, Tex.) 2011
:
E2F1 deficiency also impairs RPA and Rad51 foci formation indicating that E2F1 is important for DNA end resection and the formation of single stranded DNA at DSBs