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TGFB1 — VIM

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• STRING interaction: TGFB1 — VIM (interaction, mapped from mint intact)
• STRING interaction: VIM — TGFB1 (interaction, mapped from mint intact)

Text-mined interactions from Literome

Pagan et al., J Hepatol 1999 : Western blotting analysis showed that TGF-beta1 decreased cytokeratin and increased vimentin levels, while DMSO decreased both cytokeratin and vimentin ... When DMSO or TGF-beta1 was added in combination with EGF or HGF, both factors maintained the increase in albumin and cytokeratin induced by the growth factors although DMSO, but not TGF-beta1 , inhibited vimentin expression
Wu et al., Biochim Biophys Acta 2007 : TGFbeta1 regulation of vimentin gene expression during differentiation of the C2C12 skeletal myogenic cell line requires Smads, AP-1 and Sp1 family members ... Here, we suggest a mechanism to explain how TGFbeta1 contributes to the up-regulation of vimentin expression while blocking myogenesis
Paccione et al., Mol Cancer Ther 2008 (Carcinoma, Squamous Cell...) : Vimentin expression was enhanced by epidermal growth factor and transforming growth factor-beta both independently and in combination
Dudas et al., Nephrol Dial Transplant 2009 : In RPTEC and HK-2 cells, TGF-beta1 significantly reduced e-cadherin expression and significantly increased vimentin , CTGF and TGF-beta1 expression
Nishida et al., FEBS Lett 2009 : A possible role of vimentin on the cell surface for the activation of latent transforming growth factor-beta
Leung et al., J Clin Immunol 2009 (Kidney Failure, Chronic...) : Incubation of HPMC with recombinant NGAL reversed the transforming growth factor-beta induced up-regulation of Snail and vimentin but rescued the down-regulation of E-cadherin
Zhang et al., Clin Cancer Res 2009 (Neoplasm Recurrence, Local...) : Nuclear factor-kappaB mediated transforming growth factor-beta induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy
Villar et al., Int J Cancer 2010 : SP cells under TGF-beta1 treatment were unable to display the EMT, since the overexpression of Spred2 abolished the TGF-beta1 induced disruption of the E-cadherin cell to cell interactions, reorganization of the actin cytoskeleton and upregulation of the mesenchymal marker vimentin
Iwatsuki et al., Ann Surg Oncol 2010 (Adenocarcinoma...) : Furthermore, induction of VIM expression by TGF-beta1 and hypoxia was evaluated in gastric cancer cells
Pagan et al., Exp Cell Res 1997 : Both EGF and TGF-beta1 also induced vimentin expression in cytokeratin positive cells but this effect was not correlated with a change of epithelial phenotype