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PRL — TNF

Text-mined interactions from Literome

DeVito et al., J Cell Biochem 1999 : We have recently shown that whereas ethanol does not inhibit PRL receptor binding, it markedly inhibits PRL induced mitogenesis and TNF alpha secretion in cultured astrocytes
DeVito et al., J Cell Biochem 2000 (Astrocytoma...) : Further, we found that PRL induced ICAM-1 expression was, at least in part, due to a PRL induced increase in TNF-alpha syntheses and secretion
Theas et al., Endocrine 2000 : Because anterior pituitary function depends on hormonal environment, we also investigated the influence of gonadal steroids in the effects of TNF-alpha on cell proliferation and the release of PRL from anterior pituitary cells ... These results indicate that TNF-alpha plays an inhibitory role in anterior pituitary cell growth and the release of PRL in an estrogen dependent manner
Theas et al., Neuroendocrinology 2001 : Nitric oxide mediates the inhibitory effect of tumor necrosis factor-alpha on prolactin release ... Since NO directly inhibits prolactin secretion, we investigated the involvement of NO in the inhibitory effect of TNF-alpha on prolactin release from anterior pituitary cells of female rats ... The current results indicate that NO is involved in the inhibitory effect of TNF-alpha on prolactin secretion and that TNF-alpha induces iNOS transcription and stimulates NO synthesis in anterior pituitary cells
Mastronardi et al., Neuroimmunomodulation 2001 : The suppressive action of bromoergocryptine, a dopamine D2 receptor agonist, on LPS induced TNF-alpha release may be mediated in part by suppression of prolactin release, which triggers TNF-alpha release
Candolfi et al., Endocrinology 2002 : We previously reported that TNF-alpha reduces anterior pituitary cell proliferation and PRL release in an estrogen dependent manner
De Laurentiis et al., Neuroimmunomodulation 2002 (Bacterial Infections...) : This increase in dopaminergic activity could mediate the inhibitory effect of LPS and TNF-alpha on prolactin release
Huang et al., J Cell Biochem 2003 (Hyperprolactinemia) : These observations correlate with in vivo conditions, where prolactin increases the release of TNF-alpha by testicular interstitial macrophages, which, in turn, decreases the human chorionic gonadotropin stimulated release of testosterone by Leydig cells
Dimitrov et al., Brain Behav Immun 2004 : The following changes reached significance ( p < .05 ) : prolactin ( versus prolactin antibody ) increased tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) producing CD4+ and CD8+ cells and interleukin-2 (IL-2) producing CD8+ cells
Candolfi et al., Neuroendocrinology 2004 : Also, we showed that nitric oxide ( NO ) mediates the inhibitory effect of TNF-alpha on prolactin release
Lau et al., Immunol Lett 2006 (Diabetes Mellitus, Experimental) : Prolactin regulation of the expression of TNF-alpha , IFN-gamma and IL-10 by splenocytes in murine multiple low dose streptozotocin diabetes
Friedrichsen et al., Endocrinology 2006 : Tumor necrosis factor-alpha activates the human prolactin gene promoter via nuclear factor-kappaB signaling ... Here we show that the important cytokine TNF-alpha activates prolactin gene transcription in pituitary GH3 cells stably expressing luciferase under control of 5 kb of the human prolactin promoter ... Similar regulation of the endogenous rat prolactin gene by TNF-alpha in GH3 cells was confirmed using real-time PCR
Gerlo et al., J Neuroimmunol 2006 (Leukemia, Myeloid) : Tumor necrosis factor-alpha activates the extrapituitary PRL promoter in myeloid leukemic cells
Yang et al., Int Immunopharmacol 2006 : In addition, PRL increased the expressions of IL-6, IL-10, IL-12 and TNF-alpha in SDCs
Tripathi et al., Mol Immunol 2007 (MAP Kinase Signaling System) : PRL or GH induced TNF-alpha production by murine macrophages was insensitive in the presence of competitive inhibitor of NOS, L-NMMA ... Similarly, there is no autocrine or paracrine effect of TNF-alpha on GH or PRL induced NO production and iNOS expression
Yamaguchi et al., Endocrinol Jpn 1991 : Effect of TNF-alpha on prolactin secretion from rat anterior pituitary and dopamine release from the hypothalamus : comparison with the effect of interleukin-1 beta ... The effects of human recombinant interleukin-1 beta and -6 and tumor necrosis factor-alpha (TNF-alpha) on the releases of PRL and dopamine were examined using monolayer cultures of rat pituitary cells and hypothalamic cells ... The release of PRL from rat pituitary cells in 30 min was increased about 2-fold ( p less than 0.05 ) by 10 ( 5 ) U/l interleukin-1 beta, 10 ( 5 ) U/l interleukin-6 or 100 micrograms/l TNF-alpha ... TNF-alpha at 100 micrograms/l significantly increased PRL release within 5 min incubation and this effect continued throughout the next 30 min of incubation
Tripathi et al., Int Immunol 2008 : We have previously reported that prolactin (PRL) induces the production of nitric oxide ( NO ) and tumor necrosis factor (TNF)-alpha in murine peritoneal macrophages ... Further, pre-treatment of macrophages with SP600125 inhibited the PRL induced production of IFN-gamma and TNF-alpha ... AG490, inhibitor of JAK2, down-regulated transcription factors c-jun and STAT1 and inhibited the PRL induced IFN-gamma, TNF-alpha , IL-1 beta and IL-12p40 production in macrophages
Sodhi et al., Growth Factors 2008 (Calcium Signaling...) : The involvement of Ca++ signaling and p42/44 MAP kinase in regulation of PRL induced IL-1beta and TNF-alpha production by macrophages has also been investigated
Koike et al., Endocrinology 1991 : Tumor necrosis factor-alpha increases release of arachidonate and prolactin from rat anterior pituitary cells ... TNF alpha significantly increased the release of both PRL and [ 3H ] arachidonate release in a time- and dose dependent manner ... TNF alpha potentiated the release of [ 3H ] arachidonate and PRL promoted by phospholipase-A2 and melittin, and markedly shifted the dose-response curve to the left ... Inhibitors of phospholipase-A2, such as p-bromophenacyl bromide and quinacrine, had no effect on TNF alpha induced [ 3H ] arachidonate and PRL release ... BW755C, an inhibitor of the conversion of arachidonate to its metabolites, decreased TNF alpha induced PRL release, while indomethacin, a prostaglandin synthesis inhibitor, had no effect on TNF alpha induced PRL release ... These data indicate that arachidonate metabolites may be involved in the process of TNF alpha induced PRL release
Koike et al., Endocrinology 1991 : Tumor necrosis factor-alpha stimulates prolactin release from anterior pituitary cells : a possible involvement of intracellular calcium mobilization ... To define the role of calcium in TNF alpha induced PRL release, dispersed pituitary cells were exposed to agents that modify TNF alpha induced calcium mobilization ... Such calcium channel blockers as cobalt and verapamil decreased basal and TNF alpha induced PRL release ... A low calcium medium also decreased TNF alpha induced PRL release ... These data suggest that intracellular calcium mobilization may be involved in the process of TNF alpha induced PRL release
Walton et al., Am J Physiol 1990 : Tumor necrosis factor-alpha and interferon-gamma reduce prolactin release in vitro ... Overall prolactin accumulation during this first 24 h was inhibited by TNF-alpha and markedly reduced by TNF-alpha plus IFN-gamma
Gaillard et al., Endocrinology 1990 : Similarly, TNF alpha inhibited the stimulated release of GH ( 100 % inhibition ), LH ( 35 % inhibition ), and PRL ( 100 % inhibition ) ... TNF alpha had no effect on the basal secretion of GH or LH but inhibited basal PRL in a dose dependent manner
Milenkovic et al., Proc Natl Acad Sci U S A 1989 : The stimulation of Prl release by cachectin in the presence of somatostatin may be related to the elevation of cyclic AMP, a known stimulator of Prl release
Inoue et al., Hum Reprod 1994 : Of these cytokines, TNF alpha significantly suppressed prolactin production in a dose dependent manner, with no apparent effect on cell number ... TNF alpha and IL-1 significantly suppressed cAMP stimulated prolactin production by endometrial stromal cells ... These results indicated that TNF alpha and IL-1 suppress both progesterone induced and cAMP mediated prolactin production in endometrial stromal cells, and that this inhibition was not attributable to direct effects on progesterone metabolism or related to Ca ( 2+ ) -mediated signal transduction
Jikihara et al., Endocrinology 1994 : Tumor necrosis factor-alpha inhibits the synthesis and release of human decidual prolactin
Benedetto et al., Pathol Biol (Paris) 1995 (Toxoplasmosis, Animal...) : These data suggest that PRL can regulate in vivo endogenous TNF-alpha production in the cytokine cascade
DeVito et al., Endocrinology 1997 (Prenatal Exposure Delayed Effects) : The aim of this study was to examine the effects of ethanol on PRL induced mitogenesis and TNF alpha expression in cultured rat astrocytes ... PAE during the last 5 days of gestation blunted the PRL induced increase in [ 3H ] thymidine incorporation and TNF alpha levels in cells grown in the absence of ethanol in the culture medium ... Addition of ethanol to primary PAE astrocyte cultures resulted in a modest increase in basal [ 3H ] thymidine incorporation, but completely blocked the PRL induced increase in [ 3H ] thymidine incorporation and TNF alpha levels ... Together, these data indicate that ethanol blocks PRL induced mitogenesis and the expression of TNF alpha in cultured rat astrocytes and are consistent with the possible inhibition of the astrocytic response by ethanol in vivo
Theas et al., Endocrine 1998 : The presence of lipopolysaccharide ( LPS, 0.1 microg/mL ) in the culture medium significantly increased TNF-alpha release and inhibited prolactin release ... We also investigated the effect of TNF-alpha on prolactin release ... The presence of TNF-alpha ( 50 ng/mL ) in the culture medium inhibited prolactin release from anterior pituitary cells