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CD79A — TFRC
Text-mined interactions from Literome
Moura et al., J Am Soc Nephrol 2004
(Glomerulonephritis, IGA) :
IgA1 binding was significantly
inhibited ( > 50 % ) by soluble forms of both
TfR1 and TfR2, confirming that TfR serves as mesangial IgA1 receptor
Moura et al., J Am Soc Nephrol 2005
(Glomerulonephritis, IGA) :
Finally, upregulation of
TfR expression induced by sera from patients with IgAN but not from healthy individuals was
dependent on
IgA
Moura et al., Semin Nephrol 2008
(Disease Models, Animal...) :
Polymeric
IgA1 binding
enhances mesangial cell
TfR expression and results in cell proliferation and inflammatory and profibrogenic cytokine and chemokine production, suggesting a pivotal role in mesangial cell proliferation, matrix expansion, and recruitment of inflammatory cells
Li et al., J Biol Chem 1997
:
Syk is required for
BCR mediated
activation of
p90Rsk , but not p70S6k, via a mitogen activated protein kinase independent pathway in B cells