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IFNG — ITGAX
Text-mined interactions from Literome
Behboudi et al., Cell Immunol 2004
:
In vitro, depletion of
CD11c ( + ) DCs from mouse splenocytes, immunised with recombinant vaccinia virus Ankara ( MVA ) expressing pb9 epitope, significantly
reduced the generation of pb9-specific
IFNgamma producing effector CD8 T cells, indicating that splenic DCs are involved in the development of pb9-specific IFNgamma producing effector cells
Su et al., Infect Immun 2005
(Malaria...) :
Splenic
CD11c ( + ) dendritic cells ( DC ) from mice infected with malaria alone and coinfected mice showed similarly increased expression of CD40, CD80, and CD86, but DC from coinfected mice were unable to
induce CD4 ( + ) T-cell proliferation and optimal
IFN-gamma production in response to the malaria antigen in vitro
Kvale et al., Blood 2007
:
In contrast,
CD11c ( + ) DCs
induce IFN-gamma and little IL-10
Koizumi et al., Immunol Lett 2008
:
S-PT84
induced IFN-gamma producing cells through activation of IL-12 production by
CD11c ( + ) DCs in Toll-like receptor (TLR) 2- and/or TLR4 dependent manner
Schreiber et al., PloS one 2010
(Granuloma...) :
As a consequence of their phenotype,
CD11c ( + ) cells from chronic lesions were unable to support the reactivation of newly recruited, antigen 85B-specific CD4 ( + ) IFNgamma ( + ) T cells or
induce an
IFNgamma response from naïve T cells in vivo and ex vivo