Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Gupta et al., J Biol Chem 1999 : Our results demonstrated that : ( i ) PGN induced phosphorylation of the transcription factors ATF-1 and CREB; (ii) ATF-1 and CREB bound DNA as a dimer and induced transcriptional activation of a CRE reporter plasmid, which was inhibited by dominant negative CREB and ATF-1 ; ( iii ) PGN induced phosphorylation of c-Jun , protein synthesis of JunB and c-Fos, and transcriptional activation of the AP-1 reporter plasmid, which was inhibited by dominant negative c-Fos ; and ( iv ) PGN induced activation of CREB/ATF and AP-1 was mediated through CD14
Jeon et al., Immunopharmacology 2000 : Treatment of DEX to RAW 264.7 cells induced a dose related inhibition of NF-kappaB/Rel and AP-1 in chloramphenicol acetyltransferase activity, while neither NF-IL6 nor CREB/ATF activation was affected by DEX
Hsu et al., Mol Cell Biol 1992 : LRF-1/c-Jun, c-Fos/c-Jun , and c-Fos/JunB activate specific AP-1 and ATF site containing promoters, and in contrast, LRF-1/JunB potently represses c-Fos- and c-Jun mediated activation of these promoters
Samten et al., J Immunol 2008 : Additionally, ATF-2 controls expression of CREB and c-Jun during T cell activation