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ID2 — SMN1

Text-mined interactions from Literome

Tajima et al., Hepatology research : the official journal of the Japan Society of Hepatology 2007 : Real-time reverse transcription-polymerase chain reaction analysis showed Id2 induction significantly suppressed alpha-SMA , collagen-1, matrix metalloproteinase (MMP)-2, and MMP-9 mRNA ( P < 0.05 ) but had no effect on tissue inhibitor of metalloproteinase or transforming growth factor-beta1 levels
Veerasamy et al., PloS one 2013 : TGFß1 mediated Id2 suppression was essential for a-SMA induction in PTECs ... Although BMP7 abolished TGFß1 mediated a-SMA expression by restoring Id2 levels, the loss of Id2 was not sufficient to induce a-SMA expression even in the context of reduced E-cadherin expression ... Hence, a reduction in Id2 is critical for TGFß1 induced a-SMA expression in this model of human PTECs but is not sufficient in it self to induce a-SMA even in the context of reduced E-cadherin