Gene interactions and pathways from curated databases and text-mining

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HMOX1 — STAT3

Text-mined interactions from Literome

Ricchetti et al., J Leukoc Biol 2004 (Inflammation) : Heme oxygenase 1 expression induced by IL-10 requires STAT-3 and phosphoinositol-3 kinase and is inhibited by lipopolysaccharide
Zhang et al., FASEB J 2006 (Hyperoxia...) : Our results demonstrate 1 ) the importance of the endothelium in lethal hyperoxic injury, 2 ) HO-1 and CO require endothelial STAT3 for their protective effects, and 3 ) STAT3 confers endothelial cell protection via both HO-1 dependent and independent mechanisms
Ke et al., J Hepatol 2012 (Disease Models, Animal...) : These findings underscore the role of HO-1 induced STAT3 in modulating PI3K/PTEN in liver IRI cascade
Liu et al., PloS one 2012 (Malaria) : Then, we further determined the mechanisms how STAT3 regulates HO-1 and CXCL10 as well as mutual regulation among them in CRL-2581, a murine endothelial cell line ... ( 4 ) HO-1 regulates STAT3 signaling