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CAV1 — TNF
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Sun et al., Eur Biophys J 2002
:
As a comparison,
tumor necrosis factor-a induced a decrease of
caveolin-1 in the cells
Sun et al., Biorheology 2003
(Mechanotransduction, Cellular) :
In contrast,
TNF-alpha induced a decrease of
caveolin-1 in cells
Fawzi-Grancher et al., Clin Hemorheol Microcirc 2005
:
Role of Ca2+ in the
effects of shear stress and
TNF-alpha on
caveolin-1 expression ... In contrast,
TNF-alpha induced a decrease of
caveolin-1 in the cells, whatever the [ Ca2+ ] i
Wang et al., Am J Respir Cell Mol Biol 2006
(Inflammation) :
Loss-of-function experiments using small interfering RNA showed that down regulating
caveolin-1 expression in murine alveolar and peritoneal macrophages
increased LPS induced proinflammatory cytokine
TNF-alpha and IL-6 production but decreased anti-inflammatory cytokine IL-10 production
Fakhrzadeh et al., Toxicol Appl Pharmacol 2008
(Pneumonia) :
Regulation of
caveolin-1 expression, nitric oxide production and tissue injury by
tumor necrosis factor-alpha following ozone inhalation ... These data, together with our findings that
TNFalpha suppressed
caveolin-1 expression in cultured AM, suggest that TNFalpha and downstream signaling mediate activation of NF-kappaB and the regulation of inflammatory genes important in ozone toxicity, and that this process is linked to caveolin-1
Wang et al., Metabolism 2008
:
Caveolin-1 was significantly
induced by
TNF-alpha , which was further amplified by linoleic acid and blocked by alpha-linolenic acid
Sathish et al., Eur Respir J 2012
(Asthma...) :
Cav-1 overexpression significantly
increased Orai1 expression and SOCE, especially in the presence of
TNF-a
Shao et al., PloS one 2013
:
Rac1 inhibitors significantly abolished this barrier-protective effect induced by down-regulation of
caveolin-1 in
response to
TNF-a in RPMVECs