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PLG — TNF

Text-mined interactions from Literome

Sakamoto et al., Am J Physiol 1999 : TNF-alpha and insulin, alone and synergistically, induce plasminogen activator inhibitor-1 expression in adipocytes
Peiretti et al., J Biol Chem 2001 : Inhibition of p70 ( S6 ) kinase during transforming growth factor-beta 1/vitamin D ( 3 ) -induced monocyte differentiation of HL-60 cells allows tumor necrosis factor-alpha to stimulate plasminogen activator inhibitor-1 synthesis
Kobayashi et al., Eur J Biochem 2002 (Bone Neoplasms...) : Our laboratory showed that bikunin, a Kunitz-type protease inhibitor, suppresses 4beta-phorbol 12-myristate 13-acetate ( PMA ) - or tumor necrosis factor-alpha (TNFalpha) induced urokinase-type plasminogen activator ( uPA ) expression in different cell types
Montes et al., Thromb Haemost 2002 (Disseminated Intravascular Coagulation...) : The endotoxin induced plasminogen activator inhibitor-1 increase in rabbits is not tumor necrosis factor-alpha dependent and can occur in the absence of interleukin-1beta
Pandey et al., Am J Pathol 2003 : Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1
Gyetko et al., J Leukoc Biol 1992 : We determine how recombinant interferon-gamma (IFN) and tumor necrosis factor-alpha (TNF) regulate plasminogen activation in monoblast-like U937 cells and normal human monocytes ... To determine the relative abilities of IFN and TNF to either promote or inhibit plasmin generation, we directly compared the effects IFN and TNF, using optimal stimulating concentrations
Vairo et al., J Cell Physiol 1992 : TNF alpha and LPS inhibited both CSF-1 stimulated urokinase-type plasminogen activator ( u-PA ) mRNA levels and u-PA activity in BMM, whereas IFN gamma lowered only the u-PA activity
Logan et al., J Natl Cancer Inst 1992 (Neoplasms) : The release of tissue-type plasminogen activator was preceded by granulocytopenia, which may indicate an association between a proposed TNF induced granulocyte-endothelial interaction in vivo and release of tissue-type plasminogen activator
Hamaguchi et al., J Pharmacol Exp Ther 2003 : Tumor necrosis factor-alpha and troglitazone regulate plasminogen activator inhibitor type 1 production through extracellular signal regulated kinase- and nuclear factor-kappaB dependent pathways in cultured human umbilical vein endothelial cells
Min et al., Biochem Biophys Res Commun 2003 : Plasminogen induced IL-1beta and TNF-alpha production in microglia is regulated by reactive oxygen species
Pandey et al., FASEB J 2005 : Molecular mechanisms of tumor necrosis factor-alpha mediated plasminogen activator inhibitor-1 expression in adipocytes
Ulfhammer et al., Journal of thrombosis and haemostasis : JTH 2006 (Cardiovascular Diseases...) : TNF-alpha mediated suppression of tissue type plasminogen activator expression in vascular endothelial cells is NF-kappaB- and p38 MAPK dependent
van der Poll et al., J Exp Med 1991 : TNF induced a brief fourfold increase in the overall plasma plasminogen activator (PA) activity peaking after 1 h ( p less than 0.0001 ), which was associated with rises in the antigenic levels of urokinase-type plasminogen activator ( p less than 0.0001 ) and tissue-type plasminogen activator ( p less than 0.0001 )
Churg et al., Am J Respir Cell Mol Biol 2007 : Hirudin, a thrombin inhibitor, and aprotinin, an inhibitor of plasmin, reduced smoke mediated TNF-alpha and MMP-12 release, and A1AT inhibited both plasmin and thrombin activity in a cell-free functional assay
Niedbala et al., Biomed Biochim Acta 1991 : Tumor necrosis factor induction of urokinase-type plasminogen activator in human endothelial cells
Takeshita et al., Eur J Pharmacol 2008 (Diabetes Mellitus, Type 2...) : Cross talk of tumor necrosis factor-alpha and the renin-angiotensin system in tumor necrosis factor-alpha induced plasminogen activator inhibitor-1 production from hepatocytes
Iglesias-Osma et al., Rev Clin Esp 2008 (Cardiovascular Diseases) : Drugs as angiotensin converting enzyme inhibitors ( ACEI ), thiazolidinediones ( glitazones ) or angiotensin-II receptor antagonists, generally associated with the adequate hypolipidemic ( statins, fibrates ) or antiobesity ( orlistat, sibutramine, rimonabant ) medication, would increase those adipocytokines with anti-inflammatory and insulin sensitizing properties ( i.e. adiponectin or visfatin ), while reducing pro-inflammatory and thrombogenic cytokines ( as leptin, tumor necrosis factor [ TNF]-alpha, plasminogen activator inhibitor 1 [PAI-1 ] )
Johnson et al., J Biol Chem 1990 (Melanoma) : We examined the role of two different second messenger systems in the regulation of plasminogen activator inhibitor, type 2 ( PAI-2 ) induction by TNF in SK-MEL-109 melanoma cells
Idell et al., Am J Physiol 1994 : Conversely, TNF-alpha increased plasminogen activator (PA) activity due to increased uPA
Egawa et al., Experientia 1994 : TNF alpha increased the steady state level of urokinase-type plasminogen activator ( uPA ), and NAC inhibited this increase at a dose that also inhibited the increase in the intracellular oxidation state
Busso et al., Hepatology 1994 (Inflammation) : We show that interleukin-1 beta and tumor necrosis factor-alpha increase urokinase-type plasminogen activator production, reinforcing the concept that increased urokinase production is associated with inflammatory processes
Ng et al., J Biol Chem 1994 : Although tumor necrosis factor (TNF) and interleukin-1 ( IL ) induce the expression of the IL-8, TNF stimulated gene 6, and plasminogen activation inhibitor-2 genes and the activation of NF-kappa B with nearly identical kinetics, the two cytokines differ significantly in the induction of the IL-6 gene in all primary fibroblasts tested
Bechtel et al., Exp Cell Res 1996 : Upregulation of cell-surface associated plasminogen activation in cultured keratinocytes by interleukin-1 beta and tumor necrosis factor-alpha
Shetty et al., Am J Respir Cell Mol Biol 1996 (Pulmonary Fibrosis) : Phorbol myristate acetate, lipopolysaccharide, transforming growth factor-beta ( TGF-beta ), and tumor necrosis factor-alpha (TNF-alpha) increased uPA binding and plasminogen activation at the cell surface, with a greater maximal effect on fibrotic than on normal fibroblasts
Dear et al., Eur J Biochem 1996 : Molecular mechanisms governing tumor-necrosis-factor mediated regulation of plasminogen-activator inhibitor type-2 gene expression
Kobayashi et al., Eur J Cell Biol 1996 : The effect of UTI on tumor necrosis factor-alpha (TNF) induced stimulation of urokinase-type plasminogen activator ( uPA ) in cultured human umbilical vein endothelial cells ( HUVEC ) and in the promyeloid leukemia U937 cells was studied
Murdoch et al., J Reprod Fertil 1998 : It has been hypothesized that plasmin regulates these two responses by activating collagenases and tumour necrosis factor alpha (TNF-alpha) , respectively