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PARP1 — RAPGEF2

Text-mined interactions from Literome

Gao et al., J Biol Chem 2001 : In accordance with this, RA-GEF-2 colocalizes with activated M-Ras in the plasma membrane in COS-7 cells, suggesting a role of RA-GEF-2 in the regulation of Rap1 and Rap2, particularly in the plasma membrane
Yoshikawa et al., Mol Biol Cell 2007 : Here, we show that RA-GEF-2 is specifically responsible for the activation of Rap1 that mediates tumor necrosis factor-alpha (TNF-alpha) triggered integrin activation
Hisata et al., J Cell Biol 2007 : PDZ-GEF1 is activated by GTP-Rap1 via a positive feedback mechanism ... Thus, the interaction of PDZ-GEF1 with an internalized neurotrophin receptor transported to late endosomes induces sustained activation of both Rap1 and ERK and neurite outgrowth
Letschka et al., Blood 2008 : After T-cell activation, the direct phosphorylation of RapGEF2 at Ser960 by PKC- theta regulates Rap1 activation as well as LFA-1 adhesiveness to ICAM-1