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GZMB — RELA
Text-mined interactions from Literome
Zhou et al., Toxicological sciences : an official journal of the Society of Toxicology 2003
:
Pyrrolidine dithiocarbamate ( PDTC ) and N-tosyl-L-phenylalanine chloromethyl ketone ( TPCK ) blocked
NFkappaB and AP-1 binding activity in nuclear extracts of IL-2 stimulated NK cells in an EMSA and also
inhibited the IL-2 induced expression of perforin, granzyme A, and
granzyme B gene expression in enriched NK cells
Amtmann et al., Drugs Exp Clin Res 2003
(Endotoxemia) :
C11AG blocked LPS stimulated sphingomyelin degradation and
NF kappa B activation without interfering with p42 tyrosine phosphorylation
Zordoky et al., Curr Drug Metab 2009
(Inflammation) :
First,
NF-kappaB can directly
regulate the expression of CYP1A1, CYP2B1/2,
CYP2C11 , CYP2D5, CYP2E1, CYP3A7, and CYP27B1 through binding to the promoter region of these genes