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CCND2 — MYLIP

Text-mined interactions from Literome

Yang et al., Circ Res 2011 (Cardiomegaly...) : miR-98 decreased both expression of cyclin D2 and the activity of a cyclin D2 3'UTR luciferase reporter, suggesting that both Trx1 and miR-98 negatively regulate cyclin D2
Lu et al., Cancer Res 2011 (Nasopharyngeal Neoplasms) : Interestingly, cyclin D2 was regulated by miR-26a but not by EZH2, revealing cyclin D2 as another direct yet mechanistically distinct target of miR-26a
Yadav et al., J Biol Chem 2011 : Cotransfection studies with 3'-UTR of these genes and miRNA mimics have demonstrated that BCL2 is a direct target of miR-497 and that CCND2 is regulated negatively by either miR-302b or miR-497
Yu et al., BMC cancer 2012 (Breast Neoplasms) : MiRNA transfection and luciferase assay confirmed that bcl-2 was regulated by miR-16 and miR-143, cyclinD1 was modulated by miR-16
Li et al., Blood 2013 (Leukemia, Myeloid, Acute) : Suppression of miR-193a expands the oncogenic activity of the fusion protein AML-ETO, because miR-193a represses the expression of multiple target genes, such as AML1/ETO, DNMT3a, HDAC3, KIT, CCND1 , and MDM2 directly, and increases PTEN indirectly
Zhou et al., Biochem Biophys Res Commun 2013 (Breast Neoplasms) : Interestingly, Luciferase assays first revealed that miR-206 inhibited cyclinD2 expression by targeting two binding sites in the 3'-untranslated region of cyclinD2 mRNA
Guo et al., Oncol Rep 2013 : Furthermore, the overexpression of miR-708 reduced the expression of Akt1, CCND1 , MMP2, EZH2, Parp-1 and Bcl2 in A172 and T98G cells