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CRK — WNK1
Text-mined interactions from Literome
El-Bikai et al., Arthritis Res Ther 2010
(Osteoarthritis) :
It
inhibited a1ß1 integrin and Col II expression as well as ERK1/2 and
NF-?B-p65 phosphorylation, but, in contrast, markedly elicited PGE2 release, COX-2 expression and
p38 MAPK phosphorylation
Kim et al., J Med Food 2011
:
PCP increased the degradation of inhibitor of nuclear factor-?B ( NF-?B ) a/ß, which enhanced the nuclear translocation of NF-?B
p50/p65 and
induced the phosphorylation of extracellular signal regulated kinase, c-Jun N-terminal kinase, and
p38 mitogen activated protein kinases, which are signaling molecules downstream of TLR4