◀ Back to JUN

BTK — JUN

Pathways - manually collected, often from reviews:

• NCI Pathway Database Fc-epsilon receptor I signaling in mast cells: Btk (BTK) → JUN/FOS complex (FOS-JUN) (modification, activates) Kawakami et al., J Immunol 2000, Hata et al., J Biol Chem 1998
  Evidence: assay, other species

Text-mined interactions from Literome

Inabe et al., FEBS Lett 2002 (Agammaglobulinemia) : Recent studies have shown that Btk plays an important role in BCR mediated c-Jun NH ( 2 ) -terminal kinase ( JNK ) 1 activation ; however, the mechanism by which Btk participates in the JNK1 response remains elusive
Schmidt et al., J Immunol 2006 : This phenotype correlates with Btk dependent induction of NF-kappaB and AP-1 DNA binding activity, and altered commensal bacteria populations
Hata et al., J Biol Chem 1998 : Consistent with our previous data indicating that Btk regulates stress activated protein kinases, c-Jun N-terminal kinase (JNK) , c-Jun and other JNK-regulatable transcription factors are activated by FcepsilonRI cross linking in a Btk dependent manner