de Ruiter et al., Mol Cell Biol 2000
:
Ral dependent regulation of c-Jun phosphorylation includes JNK, a still elusive JNKK, and possibly Src
Okan et al., Oncogene 2001
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Here we show that uPAR transcription is stimulated by V12 H-Ras, the effector loop mutant V12 H-Ras G37 and constitutively-active RalA 72L. RalA dependent transcription required the presence of the ATF2-like AP1-site at -70 bp and the c-Jun binding motif at -184 bp in the uPAR promoter
de Gorter et al., J Immunol 2007
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Furthermore, while not involved in NF-kappaB activation, Ras and Ral mediate BCR controlled activation of JUN/ATF2 and NFAT transcription factors