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CALM1 — FKBP8

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: FKBP8 — CALM1 Edlich et al., EMBO J 2005
• IRef Bind_translation Interaction: FKBP8 — CALM1 (coimmunoprecipitation) Edlich et al., EMBO J 2005
• IRef Bind_translation Interaction: FKBP8 — CALM1 (affinity chromatography technology) Edlich et al., EMBO J 2005
• IRef Bind_translation Interaction: FKBP8 — CALM1 (experimental interaction detection) Edlich et al., EMBO J 2005
• IRef Biogrid Interaction: FKBP8 — CALM1 (direct interaction, pull down) Edlich et al., J Biol Chem 2007
• IRef Biogrid Interaction: FKBP8 — CALM1 (association, x-ray crystallography) Edlich et al., J Biol Chem 2007*
• IRef Biogrid Interaction: FKBP8 — CALM1 (direct interaction, pull down) Edlich et al., EMBO J 2005
• IRef Biogrid Interaction: FKBP8 — CALM1 (direct interaction, pull down) Edlich et al., J Biol Chem 2007*
• IRef Biogrid Interaction: FKBP8 — CALM1 (physical association, affinity chromatography technology) Edlich et al., EMBO J 2005
• MIPS CORUM HSP90-FKBP38-CAM-Ca(2+) complex: HSP90-FKBP38-CAM-Ca(2+) complex complex (CALM2-CALM3-CALM1-FKBP8-HSP90AA1-HSP90AB1) Edlich et al., J Biol Chem 2007
• MIPS CORUM CALM1-FKBP38-BCL2 complex: CALM1-FKBP38-BCL2 complex complex (BCL2-CALM2-CALM3-CALM1-FKBP8) Edlich et al., EMBO J 2005
• IRef Corum Interaction: Complex of CALM1-HSP90AB1-HSP90AB1-HSP90AA1-HSP90AA1-CALM1-FKBP8-FKBP8 (association, classical fluorescence spectroscopy) Edlich et al., J Biol Chem 2007
• IRef Corum Interaction: Complex of BCL2-CALM1-FKBP8 (association, coimmunoprecipitation) Edlich et al., EMBO J 2005
• IRef Innatedb Interaction: FKBP8 — CALM1 (unknown, -) Edlich et al., J Biol Chem 2007*
• IRef Intact Interaction: Complex of 306 proteins (association, pull down) Komarova et al., Mol Cell Proteomics 2011
• IRef Intact Interaction: FKBP8 — CALM1 (physical association, anti bait coimmunoprecipitation) Weiwad et al., FEBS Lett 2005
• IRef Intact Interaction: FKBP8 — CALM1 (physical association, pull down) Weiwad et al., FEBS Lett 2005

Text-mined interactions from Literome

Edlich et al., EMBO J 2005 : FKBP38 proapoptotic function mediated by this interaction is abolished by either potent inhibitors of the PPIase activity of the Ca2+/calmodulin/FKBP38 complex or RNA interference mediated depletion of FKBP38 , promoting neuronal cell survival
Edlich et al., J Biol Chem 2006 (Brain Ischemia...) : Here we show that neurotrophic FKBP ligands, such as GPI1046 and N- [ methyl ( ethoxycarbonyl ) ] cycloheximide, inhibit the calmodulin/Ca ( 2+ ) ( CaM/Ca(2+) ) -regulated FKBP38 with up to 80-fold higher affinity than FKBP12
Edlich et al., J Biol Chem 2007 : A novel calmodulin-Ca2+ target recognition activates the Bcl-2 regulator FKBP38