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MSC — TNF

Text-mined interactions from Literome

Zheng et al., Rheumatology (Oxford) 2008 (Arthritis, Rheumatoid) : The effects of both MSCs and MSC-chondrocytes on the proliferation, activation-antigen expression ( CD69 and CD25 ) and cytokine production [interferon-gamma ( IFN-gamma ), tumour necrosis factor-alpha (TNF-alpha) , interleukin (IL)-10 and IL-4 ] of CII-reactive T cells in RA patients were investigated with the stimulation of CII or otherwise
Wang et al., Surgery 2009 : Conversely, the effects of TNF-alpha and/or TGF-alpha on MSC VEGF production were significantly decreased, and MEK/ERK activation was negated in cells transfected TNFR2 siRNA
Cho et al., J Cell Physiol 2010 (Calcinosis) : Although TNF-alpha inhibits the mineralization of osteoblasts, the effect of TNF-alpha on mesenchymal stem cells (MSC) is not clear
Maggini et al., PloS one 2010 : Using mouse thioglycolate elicited peritoneal macrophages ( M ) stimulated with LPS, we found that MSC markedly suppressed the production of the inflammatory cytokines TNF-alpha , IL-6, IL-12p70 and interferon-gamma while increased the production of IL-10 and IL-12p40
Zhen et al., Cytotherapy 2010 (Disease Models, Animal...) : TNF-alpha released from papain treated lung cells induces MSC to secret VEGF-A
Wang et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2012 (Arthritis, Experimental) : It is concluded that the TNF-a exhibits different effects on immune regulation activity of MSC , and its underlying mechanism needs to further investigate