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PIK3CA — SYT1

Text-mined interactions from Literome

Rajala et al., J Virol 2005 : We demonstrate phosphorylation of GSK-3beta and nuclear translocation of the p65 subunit of NF-kappaB, both downstream targets of the PI3K/Akt pathway, in adenovirus infected corneal fibroblasts in a PI3K dependent manner
Huang et al., J Immunol 2007 : However, both JAK inhibitor I and PI3K inhibitor had no effect on the DNA binding activities of p65 and p50 to NF-kappaB consensus sequences
Zhao et al., Biochem Pharmacol 2008 : In addition, the pharmacological inhibitors of PI3K ( wortmannin and LY294002 ) enhance phosphorylation of NF-kappaB p65 on Ser529 and Ser536 residues, which result in enhanced p65 transactivation activity
Jin et al., Stroke 2011 (Infarction, Middle Cerebral Artery...) : PI3K? deficiency suppressed ischemia/reperfusion induced nuclear factor-?B p65 ( Ser536 ) phosphorylation and the expression of the pro-oxidant enzyme NADPH oxidase ( Nox1, Nox2, and Nox4 ) and proinflammatory adhesion molecules ( E- and P-selectin, intercellular adhesion molecule-1 ) at different time points