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C5AR1 — IFNG

Text-mined interactions from Literome

Burg et al., J Immunol 1995 (Lymphoma, Large B-Cell, Diffuse) : In this study, we show that in immature myelo-/monoblastic U937, HL60, and MonoMac6 cells, IFN-gamma induces C5aR-ligand binding activity ... Our data show an IFN-gamma dependent increase in C5aR expression and suggest a maturation related change in signaling of the C5aR, presumably at the level of receptor coupling
Burg et al., J Immunol 1996 : Despite comparable numbers of both receptors, IFN-gamma potentiated activation of the C5aR but not the C3aR, as measured by an increase in free cytosolic Ca2+ upon ligand activation