Gene interactions and pathways from curated databases and text-mining

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CLU — NFKB1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Saura et al., J Neurochem 2003 : Two NF-kappa B inhibitors, aspirin ( 10 mM ) and MG-132 ( 0.1 microM ), blocked basal apoE and apoJ secretion as well as LPS induced apoJ secretion
Santilli et al., J Biol Chem 2003 (Neoplasm Invasiveness) : Ectopic apolipoprotein J expression strongly inhibited NF-kappaB activity in human neuroblastoma cells and murine embryonic fibroblasts by stabilizing inhibitors of NF-kappaB ( IkappaBs )
Devauchelle et al., J Immunol 2006 (Arthritis, Rheumatoid...) : We propose that in RA joints, high levels of extracellular CLU and low expression of intracellular CLU may enhance NF-kappaB activation and survival of the synoviocytes
Savković et al., Biochem Biophys Res Commun 2007 (Disease Models, Animal...) : Presence of clusterin reduced NF-kappaB activation and expression of the NF-kappaB target genes TNF-alpha and MOB-1 under cell stress