Gene interactions and pathways from curated databases and text-mining

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NANOS2 — NFKB1

Text-mined interactions from Literome

Molina-Holgado et al., J Neurochem 2002 (Cardiovirus Infections) : The proteasome inhibitor MG-132 blocked TMEV induced nitrite accumulation, NOS-2 mRNA expression and phospho-IkappaBalpha degradation, suggesting NF-kappaB dependent NOS-2 expression
Palomba et al., J Biol Chem 2004 : Because NO suppresses the NFkappaB dependent NOS-II expression, inactivation of NOS-I by the LPS/IFNgamma induced AA pathway provides optimal conditions for NFkappaB activation and subsequent NOS-II expression ... Inhibition of cPLA2 activity, while reducing the availability of AA, consistently inhibited NFkappaB activation and NOS-II mRNA induction and delayed NO formation
Siendones et al., Hepatology 2004 : In conclusion, administration of PGE1 to hepatocytes produces low levels of NO, which inhibits its own formation during D-GalN induced cell death through the attenuation of NF-kappaB dependent NOS-2 expression
Rico et al., BMC genomics 2007 (Inflammation) : Two not previously described distal regions in rodents that are similar to the unique upstream region responsible of the NF-kappaB activation of NOS-2 in humans are fragmented and translocated to different locations in the rodent promoters