Gene interactions and pathways from curated databases and text-mining

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NFKB1 — S100B

Text-mined interactions from Literome

Lam et al., Neurobiol Aging 2001 (Alzheimer Disease) : Mechanism of glial activation by S100B : involvement of the transcription factor NFkappaB
Bianchi et al., Neurobiol Aging 2010 (Encephalitis...) : We show here that : ( 1 ) S100B also stimulates AP-1 transcriptional activity in microglia via RAGE dependent activation of JNK ; ( 2 ) S100B upregulates IL-1beta and TNF-alpha expression in microglia via RAGE engagement ; and ( 3 ) S100B/RAGE induced upregulation of COX-2, IL-1beta and TNF-alpha expression requires the concurrent activation of NF-kappaB and AP-1
Tubaro et al., J Cell Physiol 2010 : Conversely, silencing S100B expression in myoblast cell lines by RNA interference resulted in reduced NF-kappaB activity and enhanced MyoD, myogenin and MyHC expression and myotube formation