Gene interactions and pathways from curated databases and text-mining

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IFNG — REL

Text-mined interactions from Literome

Cieslik et al., Mol Pharmacol 2006 : To determine the role of C-Rel in nitric-oxide synthase-2 (NOS-2) transcriptional activation, we evaluated the effect of lipopolysaccharide and interferon-gamma ( LPS/IFNgamma ) on C-Rel DNA binding in RAW 264.7 ... LPS/IFNgamma stimulated C-Rel binding peaked at 4 to 8 h and declined at 24 h. Transfection of cells with a C-Rel small interfering RNA abrogated C-Rel binding at all time points
Jahnke et al., FEBS Lett 1994 (Melanoma) : Synergistic activation of intercellular adhesion molecule 1 ( ICAM-1 ) by TNF-alpha and IFN-gamma is mediated by p65/p50 and p65/c-Rel and interferon-responsive factor Stat1 alpha ( p91 ) that can be activated by both IFN-gamma and IFN-alpha