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IFNG — REL
Text-mined interactions from Literome
Cieslik et al., Mol Pharmacol 2006
:
To determine the role of C-Rel in nitric-oxide synthase-2 (NOS-2) transcriptional activation, we evaluated the
effect of lipopolysaccharide and
interferon-gamma ( LPS/IFNgamma ) on
C-Rel DNA binding in RAW 264.7 ...
LPS/IFNgamma stimulated
C-Rel binding peaked at 4 to 8 h and declined at 24 h. Transfection of cells with a C-Rel small interfering RNA abrogated C-Rel binding at all time points
Jahnke et al., FEBS Lett 1994
(Melanoma) :
Synergistic activation of intercellular adhesion molecule 1 ( ICAM-1 ) by TNF-alpha and
IFN-gamma is
mediated by p65/p50 and
p65/c-Rel and interferon-responsive factor Stat1 alpha ( p91 ) that can be activated by both IFN-gamma and IFN-alpha