Gene interactions and pathways from curated databases and text-mining

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KLRC1 — TNF

Text-mined interactions from Literome

Rincon-Orozco et al., J Immunol 2005 : Furthermore, NKG2D triggers the production of TNF-alpha but not of IFN-gamma, as well as the release of cytolytic granules by Vgamma9 Vdelta2 T cells
Zhou et al., J Immunol 2008 (Orthomyxoviridae Infections...) : TNF-alpha produced by Ag-specific CD8+ T cells appears primarily responsible for this immunopathology, and we have examined the negative regulation of CD8+ TNF production by CD94/NKG2A engagement with its receptor, Qa-1b ... TNF production by antiviral CD8+ T cells was significantly enhanced by NKG2A blockade in vitro, and mice deficient in the NKG2A ligand, Qa-1b, manifested significantly greater pulmonary pathology upon CD8+ T cell mediated clearance in influenza pneumonia
Gannagé et al., Transplantation 2008 (Acute Disease...) : Induction of NKG2D ligands by gamma radiation and tumor necrosis factor-alpha may participate in the tissue damage during acute graft-versus-host disease