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KLRC1 — TNF
Text-mined interactions from Literome
Rincon-Orozco et al., J Immunol 2005
:
Furthermore,
NKG2D triggers the production of
TNF-alpha but not of IFN-gamma, as well as the release of cytolytic granules by Vgamma9 Vdelta2 T cells
Zhou et al., J Immunol 2008
(Orthomyxoviridae Infections...) :
TNF-alpha produced by Ag-specific CD8+ T cells appears primarily responsible for this immunopathology, and we have examined the negative
regulation of CD8+
TNF production by
CD94/NKG2A engagement with its receptor, Qa-1b ...
TNF production by antiviral CD8+ T cells was significantly
enhanced by
NKG2A blockade in vitro, and mice deficient in the NKG2A ligand, Qa-1b, manifested significantly greater pulmonary pathology upon CD8+ T cell mediated clearance in influenza pneumonia
Gannagé et al., Transplantation 2008
(Acute Disease...) :
Induction of
NKG2D ligands by gamma radiation and
tumor necrosis factor-alpha may participate in the tissue damage during acute graft-versus-host disease