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CRP — RETN

Text-mined interactions from Literome

Hu et al., Cytokine 2007 (Atherosclerosis...) : Decreased C-reactive protein induced resistin production in human monocytes by simvastatin ... We hypothesize that CRP may result in overexpression of resistin , and statin may decrease CRP induced resistin expression in cultured human peripheral blood monocytes ( PBMC ) ... The aim of the present study, therefore, was to assess the effects of both CRP on resistin expression and simvastatin on CRP induced of resistin expression in cultured human PBMC ... The results showed that CRP induced both mRNA expression and protein secretion of resistin in a dose- and time dependent manner ... In the present study, the data showed that CRP could significantly increase resistin expression in cultured human PBMC, and this effect was inhibited by simvastatin, suggesting that CRP and resistin might be involved in the pathogenesis of atherosclerosis, and statin therapy might be beneficial for atherosclerotic disease by modifying CRP induced resistin overexpression in PBMC
Kawamura et al., Nephrol Dial Transplant 2010 (Chronic Disease...) : In stratified analyses, high resistin level ( =7.2 ng/mL ) was a significant relevant factor in CKD, independent of HOMA-IR or hs-CRP level