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CDK4 — PDGFB
Text-mined interactions from Literome
Kundumani-Sridharan et al., Am J Pathol 2007
(Carotid Artery Injuries) :
PDGF-BB induced cyclin D1 expression,
CDK4 activity, and Rb protein phosphorylation, leading to VSMC growth and motility, and these responses were suppressed by the blockade of STAT-5B
Xu et al., Clin Exp Pharmacol Physiol 2011
:
In addition, TSG significantly inhibited
PDGF-BB induced phosphorylation of Rb and the expression of cyclin D1,
CDK4 , cyclin E, CDK2 and PCNA
Liu et al., Mol Cell Biochem 2011
:
Berberine and DHEAS decreased the expression of CDK2,
CDK4 , PCNA, cyclin D1, and cyclin E, which was
induced by
PDGF-BB
Rao et al., Biochim Biophys Acta 1999
(Hyperplasia...) :
In contrast,
PDGF-BB induced depletion of p27kip1 and increased cyclins D1 and E levels and CDK2 and
CDK4 activities