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ARSA — PGF

Text-mined interactions from Literome

De La Cruz et al., Br J Pharmacol 2002 : Leucocyte 6-keto-PGF ( 1alpha ) was inhibited by ASA ( IC ( 50 ) 6.58+/-0.76 micro M ) and increased by dazoxiben and DT-TX 30
Molina et al., Prostaglandins Leukot Essent Fatty Acids 2003 (Death, Sudden...) : D-003 and ASA monotherapies reduced serum TxB ( 2 ) levels, whereas D-003, but not ASA , significantly increased 6 keto PgF1alpha levels
Birnbaum et al., Prostaglandins Other Lipid Mediat 2007 : ASA ( 50 mg/kg and 200 mg/kg, but not 10 mg/kg ) augmented the LPS effect on 15-epi-LXA4 but attenuated the effect on 6-keto-PGF ( 1alpha )
Takeuchi et al., Tohoku J Exp Med 1991 : An inhibitor against prostaglandin synthesis, acetylsalicylic acid ( ASA, 10 ( -6 ) M ) abolished BK-induced 6-keto-PGF1 alpha synthesis, whereas ASA did not affect the increase in [ Ca2+ ] i. BK-induced increases in [ Ca2+ ] i and 6-keto-PGF1 alpha production occurred in a dose dependent manner and the half-maximal response was observed at the same concentration of BK ( 10 ( -7 ) M )
Ogston et al., Int J Obes Relat Metab Disord 2008 (Obesity) : Similarly, in mice, ASA ( 0.2 and 2.0 mg kg ( -1 ) ) suppressed SC WAT 6-keto-PGF ( 1alpha ) ( a stable metabolite of prostacyclin ) and IL-6 release
Heinroth-Hoffmann et al., Biomed Biochim Acta 1988 : ASA and AR 12456 completely eliminated the second blood pressure depression after injection of AA and simultaneously diminished TXA2, TXB2 and 6-keto-PGF1a formation in murine blood, whereas BM 13177 prevented the return of the blood pressure to preinjection level after the initial brief fall in arterial pressure
Bearn et al., Int J Exp Pathol 1993 (Graft Occlusion, Vascular) : ASA + DPM significantly reduced arterial 6-keto-PGF1a although this was marginally increased by CGS12970