Gene interactions and pathways from curated databases and text-mining

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JAK3 — RELA

Text-mined interactions from Literome

Knecht et al., Oncology 2001 (Cell Transformation, Neoplastic...) : TRAF2 mediated NF-kappaB activation, AP-1 induction and JAK3/STAT activation may result in sustained proliferation leading to lymphoma
Kanda et al., Endocrinology 2007 (MAP Kinase Signaling System...) : Inhibitors of Janus kinase ( JAK ) , p38 MAPK, and MAPK/ERK kinase (MEK) suppressed prolactin- plus IFN-gamma induced CXCL9, CXCL10, and CXCL11 production and NF-kappaB , STAT1, and IRF-1 activities
Hu et al., J Leukoc Biol 2007 : Similarly, basal ITAM signaling augments IFN signaling and function of receptor activator of NF-kappaB , but extensive ITAM activation inhibits Jak-STAT signaling
Huang et al., J Immunol 2007 : Requirement for both JAK mediated PI3K signaling and ACT1/TRAF6/TAK1 dependent NF-kappaB activation by IL-17A in enhancing cytokine expression in human airway epithelial cells