Gene interactions and pathways from curated databases and text-mining

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FGF10 — ISL1

Text-mined interactions from Literome

Golzio et al., PloS one 2012 : ISL1 directly regulates FGF10 transcription during human cardiac outflow formation
Narkis et al., Dev Dyn 2012 : Fgf10 expression in the bud mesenchyme is dependent on Isl1 and its Ldb co-regulators ... Isl1/Ldb complexes regulate Fgf10 to orchestrate the earliest stages of hindlimb formation
Watanabe et al., Proc Natl Acad Sci U S A 2012 : Fibroblast growth factor 10 gene regulation in the second heart field by Tbx1, Nkx2-5, and Islet1 reveals a genetic switch for down-regulation in the myocardium ... Mutation of these sites reduces transgene expression in the anterior second heart field where the Fgf10 regulatory element is activated by Islet1 via direct binding in vivo