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MSX2 — WNT2
Text-mined interactions from Literome
Hussein et al., J Biol Chem 2003
:
Interestingly, the
Wnt/beta-catenin dependent activation of
Msx2 was defective in Smad4-deficient embryonic stem cells or when Smad binding elements were mutated but persisted in the presence of various BMP antagonists, indicating that Smad4 was involved in transducing the Wnt/beta-catenin signals in the absence of a BMP autocrine loop
Towler et al., Ann N Y Acad Sci 2006
(Calcinosis) :
Msx2 upregulates aortic
Wnt signaling in vivo, revealed by the analysis of TOPGAL+ ( Wnt reporter ) versus CMV-Msx2Tg+ ; TOPGAL+ mice
Cheng et al., J Biol Chem 2008
:
We hypothesized that
Msx2 might
activate skeletal
Wnt signaling
Zhai et al., Oncogene 2011
(Carcinoma, Endometrioid...) :
WNT pathway activation by WNT3a ligand or GSK3ß inhibitor treatment potently induced MSX2 and ectopic expression of a dominant negative form of TCF4
inhibited MSX2 expression in ovarian cancer cells