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CD40 — CRK

Text-mined interactions from Literome

Ha et al., J Immunol 2004 : We also show that the treatment of cells with inhibitors for the phosphatidylinositol 3-kinase (PI3-K) interfered with the CD40 induced ROS production and p38 activation
Davies et al., Mol Cell Biol 2005 : Interestingly, whereas the TRAF6 interacting membrane-proximal domain of CD40 has a minor role in signal transduction, studies utilizing TRAF6 knockout fibroblasts and RNA interference in epithelial cells reveal that the CD40 induced activation of NF-kappaB, JNK, p38 , and Akt requires the integrity of TRAF6
Lee et al., Journal of cell communication and signaling 2007 : We found that CD40 activated JNK, p38 , and Akt via redox dependent pathways that were sensitive to ROS depletion by NAC and ebselen
Ha et al., J Leukoc Biol 2008 : CD40 mediated activation of ERK and p38 was also minimal in these B cells of CB
Kim et al., J Med Food 2011 : PCP increased the degradation of inhibitor of nuclear factor-?B ( NF-?B ) a/ß, which enhanced the nuclear translocation of NF-?B p50/p65 and induced the phosphorylation of extracellular signal regulated kinase, c-Jun N-terminal kinase, and p38 mitogen activated protein kinases, which are signaling molecules downstream of TLR4
Sarma et al., PloS one 2012 : Depending on the strength of signal dose, CD40 receptor ( CD40 ) controls ERK-1/2 and p38MAPK activation
Blix et al., BMC cancer 2012 (Leukemia, Lymphocytic, Chronic, B-Cell...) : Similarly, CD40L induced p-ERK and p-p38 were also significantly reduced in lymphoma B cells, whereas p-p65 ( NF-?B ) was equal to that of normal B cells