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REN — SPP1
Text-mined interactions from Literome
Ricardo et al., American journal of physiology. Renal physiology 2000
(Hydronephrosis...) :
Antisense oligonucleotide inhibition of angiotensinogen and ANG II type 1 receptor ( AT(1) ) mRNA translation in rat proximal tubules ( PT ) was examined to provide direct evidence for a
role of the
renin-angiotensin system (RAS) in upregulated
osteopontin expression observed following mechanical cell stretch
Li et al., Kidney Int 2003
(Diabetes Mellitus, Type 2...) :
Osteopontin (OPN) mediates progressive renal injury in various renal diseases by attracting macrophages, and its expression is
regulated by the
renin-angiotensin system (RAS)
Wang et al., Exp Eye Res 2012
(Disease Models, Animal...) :
Effect of
SPP 635, a
renin inhibitor , on intraocular pressure in glaucomatous monkey eyes ... The effect of topical application of
SPP 635, a
renin inhibitor , on intraocular pressure ( IOP ) was evaluated in the eyes of monkeys with laser induced unilateral glaucoma ... Topically applied
SPP 635, a new
renin inhibitor , reduces IOP in glaucomatous monkeys in a dose dependent manner